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Ph.D. Lian WILLETTS Postdoctoral Fellow, Dr. John Lewis Laboratory, Department of Oncology, University of Alberta; Finalist, 2015 Falling Walls Lab Berlin; Edmonton

CV

 Postdoctoral Fellow
 Department of Oncology, University of Alberta, Edmonton, Canada 2014-Present
 " Develop and validate novel and robust ex vivo and in vivo screen for cancer metastasis
 " Develop immuno-competent animal models to study human prostate cancer metastasis
 Postdoctoral Fellow 2012-2013
 Division of Pulmonary Medicine, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona, Scottsdale, AZ, USA (Visiting Scientist)
 Develop sensitive clinical diagnostic assays for eosinophil degranulation as part of the asthma and allergy research team, and utilize mouse models to examine the role of eosinophils in allergic inflammation
 Generate and maintain complex transgenic mouse colonies for animal model-based research
 Graduate Research Fellow 2008-2012
 Pulmonary Research Group, University of Alberta, Edmonton
 Investigated the impact of eosinophil degranulation on the pathophysiology of allergic asthma
 Designed and executed in vitro, ex vivo, and in vivo assays to measure eosinophil degranulation and pulmonary pathogenesis using transgenic mouse models
 Undergraduate Student Researcher 2005-2008
 Division of Anatomy, University of Alberta, Edmonton, Canada
 Divisions of Neurosurgery and Anatomy, University of Alberta, Edmonton, Canada
 Investigated neuronal deficits of the cerebellum in ethanol-induced guinea pigs for fetal alcohol syndrome
 Assisted in the investigation of locomotion and biomechanics in primates
 Assisted in a cadaveric study of purely percutaneous C1-C2 fusion

Mitgliedschaften

Alberta Prostate Cancer Research Initiative (APCaRI)
International Eosinophil Society
University of Alberta Alumni Association
Mayo Clinic Alumni Associatio

Publikationen

Willetts L, David Bond, Konstantin Stoletov, John Lewis. Quantitative Analysis of human Cancer Cell Extravasation Using Intravital Imaging Department of Oncology, University of Alberta (2016) Methods Molecular Biology, Vol. 1458, The Tumor Microenvironment, 978-1-4939-3799-8, 332978_1_En, (3) in press.
Willetts L, Ochkur SI, Jacobsen EA, Lee JJ, Lacy P. Eosinophil shape change and secretion. (2014) Methods Mol Biol vol:1178 pg:111-128.
Willetts L, Parker K, Wesselius LJ, Protheroe CA, Jaben E, Graziano P, Lacy P, Moqbel R, Leslie KO, Lee NA, Lee JJ. Immunodetection of occult eosinophils in lung tissue biopsies may help predict survival in acute lung injury. (2011) Respir Res, 12:116.
Jacobsen EA, Lesuer WE, Willetts L, Zellner KR, Mazzolini K, Antonios N, Beck B, Protheroe C, Ochkur SI, Colbert D, Lacy P, Moqbel R, Appleton J, Lee NA, Lee JJ. Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice. (2013) Allergy.

Auszeichnungen

Falling Walls Young Innovators of the Year 2015, Berlin, Germany 2015
Prostate Cancer Research Program Postdoctoral Training Award, Department of Defense office of the Congressionally Directed Medical Research Programs 2015
AUM Science and Innovation Award, Keystone Symposium on microRNA and dsRNA in Cancer 2015
8th International TSPAN Scaffolding Research Conference, Company of Biologists Travel Award 2015