| 1981-1983 | Advisor, Minister of Economy and Finance, Jacques Delors, Paris |
| 1983-1985 | Deputy Head of Prime Minister Pierre Mauroy's cabinet, Paris |
| 1985-1994 | Head of Cabinet of the President of the European Commission Jacques Delors Cabinet, and his "sherpa" at the G-7/G-8, Brussels |
| 1994-1999 | Recovery of the French Bank Crédit Lyonnais, then Chief Executive Officer, Paris |
| 1999-2004 | Commissioner for Trade under the presidency of Romano Prodi, European Commission, Brussels |
| 2005-2013 | Director General of the World Trade Organisation, Geneva |
| since 2015 | Interministerial delegate for the preparation of the French candidature for the Universal Exhibition 2025 |
| since 2016 | President of the French Committee of the Pacific Economic Cooperation Council (PECC) |
